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Reduction of Sympathetic Hyperactivity by Agents that Inhibit the Renin Angiotensin Aldosterone System

[ Vol. 6 , Issue. 2 ]

Author(s):

Laima Siddiqi and Peter J. Blankestijn   Pages 139 - 147 ( 9 )

Abstract:


This review describes the interactions between the renin-angiotensin and the sympathetic nervous system. Secondly, conditions and disease states particularly characterized by hyperactivity of the renin-angiotensin and/or the sympathetic nervous system will be discussed and finally evidence on the effects on the sympathetic nervous system of agents that inhibit the renin-angiotensin system and the significance of these findings in our understanding of the pathogenesis of sympathetic hyperactivity are summarized.

Keywords:

Sympathetic nerve hyperactivity, renin angiotensin aldosterone system

Affiliation:

Department of Nephrology and Hypertension, University Medical Center, Room F03.226, PO Box 85500, 3508 GA Utrecht, the Netherlands.



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