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Reduction of Sympathetic Hyperactivity by Agents that Inhibit the Renin Angiotensin Aldosterone System

[ Vol. 6 , Issue. 2 ]


Laima Siddiqi and Peter J. Blankestijn   Pages 139 - 147 ( 9 )


This review describes the interactions between the renin-angiotensin and the sympathetic nervous system. Secondly, conditions and disease states particularly characterized by hyperactivity of the renin-angiotensin and/or the sympathetic nervous system will be discussed and finally evidence on the effects on the sympathetic nervous system of agents that inhibit the renin-angiotensin system and the significance of these findings in our understanding of the pathogenesis of sympathetic hyperactivity are summarized.


Sympathetic nerve hyperactivity, renin angiotensin aldosterone system


Department of Nephrology and Hypertension, University Medical Center, Room F03.226, PO Box 85500, 3508 GA Utrecht, the Netherlands.

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