Gen-Min Lin*, Kun-Zhe Tsai, Chin-Sheng Lin and Chih-Lu Han Pages 1 - 5 ( 5 )
Aim: To investigate the association of physical fitness with long-term blood pressure variability (BPV) in young male adults.
Methods: We included 1,112 healthy military males, ages 18-40 years (mean age, 32 years) in Taiwan for the current analysis. Resting blood pressures were measured over right upper arm in a sitting position every two-year interval from 2012 to 2018 (2012-14, 2014-15, 2015-16, 2016-18). We assessed long-term BPV by standard deviation (SDSBP and SDDBP) and average real variability (ARVSBP and ARVDBP) across 4 visits during the study period. Aerobic fitness was evaluated by time for a 3000-meter run test, and anaerobic fitness was evaluated by numbers of 2-minute sit-ups and 2-minute push-ups, respectively.
Results:After adjusting for systolic and diastolic blood pressure, time for a 3000-meter run was associated with ARVSBP, SDSBP, and SDDBP (β [SE]: 0.007 [0.002], 0.004 [0.002], and 0.005 [0.002], respectively, all p <0.05) but not with ARVDBP. In addition, numbers of 2-minute sit-ups were inversely associated with ARVSBP (β [SE]: -0.041 [0.017], p =0.01) but not with ARVDBP, SDSBP, and SDDBP. There was no association of numbers of 2-minute push-ups with the BPV indexes. After additionally adjusting for age, body mass index, and other covariates, all the associations were not significant.
Conclusion: We found that there was no association of physical fitness with long-term BPV in young male military personnel. Previous studies have shown no association with cardiorespiratory fitness in the elderly. This study further extended the knowledge of a null association between anaerobic fitness and long-term BPV.
Microhemorrhage, murine surrogate, ponezumab (PF-04360365), safety, Tg2576 mice, Aβ, CAA., Blood pressure variability, Physical fitness, Young male adults
Department of Preventive Medicine, Northwestern University, Chicago, IL 60611, Department of Medicine, Hualien Armed Forces General Hospital, Hualien, Departments of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Department of Medicine, Taipei Veterans General Hospital, Taipei