Submit Manuscript  

Article Details


Arterial Stiffness in Haemodialyzed Patients: Findings and Controversies

[ Vol. 14 , Issue. 2 ]

Author(s):

Edmundo Cabrera-Fischer, Yanina Zocalo, Sandra Wray and Daniel Bia*   Pages 100 - 106 ( 7 )

Abstract:


Vascular research in end-stage renal diseases is an interesting field in which the characterization of arterial stiffness proved to be valuable to predict morbidity and mortality. Particularly, patients on renal replacement therapy have been reported to have significant increases in arterial stiffness and cardiovascular mortality. The clinical relevance of the measurement of arterial stiffness is linked to therapeutical and preventive interventions. The purpose of this work is to analyze the results of the scientific research in the field of arterial stiffness, in which hemodialyzed patients were involved, emphasizing on clinical and in-vitro research carried out by our group compared to contributions previously reported in the specialized literature. These investigations are necessary to improve diagnostic strategies and monitor the arterial response to therapeutical interventions in chronic kidney disease.

Keywords:

Arterial stiffness, aortic stiffness, pulse wave velocity, hemodialysis, vascular access, chronic kidney disease.

Affiliation:

Instituto de MedicinaTraslacional, Trasplante y Bioingenieria (IMeTTyB), Universidad Favaloro-CONICET, Solis 453, C1078AAI Buenos Aires, Physiology Department, School of Medicine, Centro Universitario de Investigacion, Innovacion y Diagnostico Arterial (CUiiDARTE), Republic University, Montevideo, Instituto de MedicinaTraslacional, Trasplante y Bioingenieria (IMeTTyB), Universidad Favaloro-CONICET, Solis 453, C1078AAI Buenos Aires, Physiology Department, School of Medicine, Centro Universitario de Investigacion, Innovacion y Diagnostico Arterial (CUiiDARTE), Republic University, Montevideo

Graphical Abstract:



Read Full-Text article