Kim Turner* and Afshan B. Hameed Pages 80 - 88 ( 9 )
Background: Hypertensive disorders (preeclampsia, eclampsia, gestational hypertension, and chronic hypertension with superimposed preeclampsia) complicate 3-5% of all pregnancies and are a significant cause of maternal mortality and morbidity. Preeclampsia is a multi-system disorder characterised by new onset hypertension after the 20th week of pregnancy with proteinuria. Proteinuria is defined as 300 mg or more of protein in a 24-hour urine collection or a protein: creatinine ratio of 0.3 mg/dL using a spot urine specimen. Hypertensive disorders have a complex pathophysiology that results from abnormal placen- tation and a maternal response that develops into a clinicalsyndrome for which there is no single test or “cure”. In high income countries, low rates of maternal mortality from hy- pertensive disease in pregnancy illustrate the importance of pregnant women being able to readily access antenatal care.
Conclusion: There remains the need to develop evidence-based clinical guidelines for detection, prophylaxis and management worldwide.
Global burden of disease, pathophysiology, risk factors, reducing the risk of hypertensive disorders in pregnancy, diagnosis, complications, monitoring, management, breast feeding and anti-hypertensives, care of women in the postnatal period.
University of Southern California - Global Health Los Angeles, California, CA 90012, Department of Obstetrics, University of California Irvine - California, CA 90012